A Randomized Controlled Trial in Reducing Seroma Formation Post Modified Radical Mastectom: Harmonic Scalpel Versus Electro Cautery

Introduction solely a number of studies compare the efficaciousness of the harmonic surgical knife and thermocautery in playing mastectomies, and these have primarily compared their intraoperative parameters. however the most concern with thermocautery is that the incidence of flap mortification and seroma formation. Therefore, this study was done to work out if the harmonic surgical knife has any benefits over thermocautery in reducing surgical flap mortification and seroma formation in patients undergoing a changed mastectomy (MRM). Methodology This randomised management trial was disbursed over a annual amount during a tertiary care centre in South Asian nation. The study patients were randomised into Associate in Nursing thermocautery cluster and a harmonic surgical knife cluster. within the initial cluster, ablation as well as flap and axillary dissection was done mistreatment thermocautery. within the second cluster, a harmonic surgical knife was used for dissection. This study compared the efficaciousness of the harmonic surgical knife with thermocautery in terms of surgical seroma formation and flap mortification. numerous alternative perioperative parameters just like the range of drain days, total drain volume (in mL), operative time (in minutes), intraoperative blood loss (in mL), and surgical wound website pain were conjointly studied. throughout every surgical visit, the presence of seroma was assessed clinically, {and the|and therefore the|and conjointly the} range of aspirations needed for the seroma was also analysed. Results a complete of 240 patients were randomised into 2 teams of one hundred twenty patients every. Baseline parameters were comparable across each teams. there have been vital variations within the period of surgery [151.38 mins vs. 112.33 mins; p = zero.001] and intraoperative blood loss [276.25 mL vs.200.13 mL; p = zero.001]. On surgical Day (POD) one, the distinction within the mean pain scores [6 vs. 4; p = 0.001] was statistically vital.

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