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Genetic Polymorphic Impact of Metabolizing Enzyme (CYP3A4 and UGT1A4 genes) on Anastrazole Response in Iraqi Breast Cancer Women

1. Abstract 1.1. Background and Objective: Anastrazole is an aromatase inhibitor used widely in therapy of breast cancer and has been metabolized by CYP3A4 and UGT1A4 in liver. Breast cancer is the most common cancer type in worldwide and the second causes of death after lung cancer and the one of therapy that use in …

Genetic Polymorphic Impact of Metabolizing Enzyme (CYP3A4 and UGT1A4 genes) on Anastrazole Response in Iraqi Breast Cancer Women Read More »

Concomitant Diseases in a Complex Case of Peritonitis after Stapled Trans Anal Rectal Resection (Starr) in Obstructed Defecation Syndrome (Ods). Role of a Diagnostic and Therapeutic Multidisciplinary Approach

1. Abstract Approximately 0.06-2.3% of the population presents a Jejunal and Ileal Diverticular (JID) disease, of whom approximately 10% develop life-threatening complications such as inflammation, perforation, bleeding, obstruction, and malabsorption [1-3, 9]. Although only 40% of these patients remain asymptomatic, jejunal diverticulosis is usually not clinically suspected. The diagnosis of this condition is usually made …

Concomitant Diseases in a Complex Case of Peritonitis after Stapled Trans Anal Rectal Resection (Starr) in Obstructed Defecation Syndrome (Ods). Role of a Diagnostic and Therapeutic Multidisciplinary Approach Read More »

Mucoepidermoid Carcinoma of Parotid Gland: 2 Cases and Literature Review

1. Abstract Mucoepidermoid Carcinoma (MEC) of the salivary gland accounted for 5% of all salivary gland tumors and 20% of all malignant salivary gland tumors [1]. About 50% of salivary gland Mucoepidermoid carcinoma occurred in the parotid gland, and 45% occurred in small salivary glands of the maxillary and buccal mucosa [2]. The main age …

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A Case of Giant Intrapericardial Teratoma of the Heart in an Infant with a Favorable Outcome

1. Abstract Primary cardiac tumors in newborns and young children are rare, but they affect significantly their health and can be the cause of sudden death. These tumors compromise the integrity and function of adjacent cardiac structures, causing often impaired blood flow, causing myocardial dysfunction, valve failure, arrhythmias, respiratory changes, and cyanosis. We present a …

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Schwannoma With Extensive Vascular Hyperplasia in the Breast Mimicking Angiosarcoma

1. Abstract Schwannoma with extensive vascular hyperplasia in the breast is extremely rare. It is typically benign and slow growing. Here, we describe a case of 54-year-old woman underwent complete resection of a tumor measuring 2.5×2.0 cm in the breast. The tumor was composed with spindle cell component and abundant blood vessel component. The subcapsular …

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Solitary Gastric Metastasis of Breast Invasive Lobular Carcinoma

1. Abstract A 52-year-old female patient with solitary gastric metastasis from breast invasive lobular cancer without any other organ involvement is presented in this study. Solitary gastric metastasis of breast cancers is very rare. It can be diagnosed incidentally by endoscopic biopsy and immuno-histo-chemical analysis. Symptoms and clinical findings are not different from primary gastric …

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Mandibular AV Malformation: Life-Threatening Bleeding from the Mouth Managed by Endovascular Intervention Complicated by Acute Ischemic Stroke on Table. Case Report

1. Abstract Arteriovenous malformations (AVM) of mandibula are rare abnormal congenital vascular condition that can result in serious complications. Although, various treatment options have been advocated in the literature, there seems to be no complete consensus on a suitable treatment option in these cases. Here, we describe a case of mandibular AVM, who has presented …

Mandibular AV Malformation: Life-Threatening Bleeding from the Mouth Managed by Endovascular Intervention Complicated by Acute Ischemic Stroke on Table. Case Report Read More »

Laparoscopic Resection of Large Endo-Cervical Polyp Through Posterior Colpotomy as an Alternative Access to Vagina in Virgin Patients

1. Abstract Endometrial polyps have been involved in about 50% of patients with abnormal uterine bleeding and 35% of infertile patients. Management of pedunculated endocervical myoma or polyp normally requires intervention via the vaginal route. Laparoscopy provides safe alternative in patients demanding hymenal integrity. A 28-year-old, nulliparous virgin woman who presented with anemia secondary to …

Laparoscopic Resection of Large Endo-Cervical Polyp Through Posterior Colpotomy as an Alternative Access to Vagina in Virgin Patients Read More »

First Case of Hb Agrinio with – –SEA Causing Hb H Disease in an Individual from China: A Case Repot and Review the Literature

1. Abstract 1.1. Background: Hb Agrinio (α29(B10) Leu→Pro), is an unstable abnormal hemoglobin (Hb), which was identified in the α2-globin gene with the variant c.89T>C, and has been reported only in individuals of Greek, Cypriot, Macedonian and Spanish origin. The variant with HBA2: c.89T>C can result in an α+ allele leading to a mild degree …

First Case of Hb Agrinio with – –SEA Causing Hb H Disease in an Individual from China: A Case Repot and Review the Literature Read More »