Volume 8

The Role of Bone Mineral Density Assessment in Health-Related Quality of Life in Postmenopausal Han Chinese Women Prior to Clinic Diagnosis of Osteoporosis

1. Abstract 1.1. Purpose: Osteoporosis is a systemic skeletal disease and strongly associated with reduced quality of life (QoL). The aim of the study was to explore BMD that might serve as index of health-related QoL (HRQoL), or the relationship between bone mineral density (BMD) and HRQoL in postmenopausal Han Chinese women prior to diagnosis …

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Unerupted Teeth, A New Symptom of Amyloidosis?

1. Abstract 1.1. Background: Amyloidosis are rare diseases related to the pathological aggregation and accumulation of misfolded proteins in the extracellular space generating insoluble deposits. This may occur in almost any tissue and organ, leading to severe structural damages and functional impairments. Oral manifestations are frequent in systemic amyloidosis and represent 9% of the localized …

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Commentary: Defecation Delay in Patients After Lung Tumor Surgery: A Prospective Nested Case-Control Study

Dear Editors This is a brief commentary to our article “Defecation delay in patients after lung tumor surgery: a prospective nested case-control study” [1]. The author Chen used to be a resident and rotate in different departments of surgery and find that discomfort related to defecation is quite common in patients receiving various operation under …

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After Sequential Therapy with First and Third Generation EGFR-Tkis, A Patient Acquired EGFR G719A Mutation and Responded to Afatinib, and Then, Acquired EGFR T790M Mutation When Developed Resistance to Afatinib: A Case Report

1. Abstract NSCLC patients who had sensitive EGFR mutation had great possibility to get benefit from EGFR-TKIs. But this efficacy was relied on related EGFR mutation, if related EGFR mutation changed, resistance would happened. In our report, we did next generation sequencing(NGS) each time the patient had progression. We observed the patient acquired rare mutation …

After Sequential Therapy with First and Third Generation EGFR-Tkis, A Patient Acquired EGFR G719A Mutation and Responded to Afatinib, and Then, Acquired EGFR T790M Mutation When Developed Resistance to Afatinib: A Case Report Read More »

SARS-Cov2 and limb Ischemia

1. Abstract Patients with severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) infection mainly present severe pneumonia associated with complications related to cytokine storm syndrome. So, it was associated with thrombotic incidents like acute limb ischemia and pulmonary embolism.

A Road from Coronary to Pulmonary: A Rare Imaging Presentation

1. Abstract Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Its association with Pulmonary Atresia is considered to be the most severe form, the diagnosis of which plays an important role in determination of the treatment protocol. In such cases, systemic vascular channels called Major Aortopulmonary Collateral Arteries (MAPCA’s) develop from …

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Ulcerative Colitis with Aseptic Abscesses Controlled by Vedolizumab: A Case Report

1. Abstract 1.1. Introduction: Aseptic abscesses (AAs) are neutrophilic infiltrative lesions that often coincide with systemic inflammatory disorders such as inflammatory bowel diseases (IBD). According to recent literature, medical therapies in IBD with AAs include corticosteroid, immunosuppressants and anti-TNFα biologics. 1.2. Report: Herein we reported a patient of ulcerative colitis with AAs and other extraintestinal …

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A Metastatic Melanoma Patient with Spontaneous Melanoma-Associated Vitiligo Survived for up to 7 Years and 5 Months: A Case Report

1. Abstract 1.1. Background: Malignant melanoma is a highly malignant tumor caused by abnormal proliferation of melanoma cells in the skin and mucous membranes, with a poor prognosis after metastasis. Skin melanocytes are gradually destroyed in vitiligo patients. There is a certain correlation between these two diseases: In these two conditions, cytotoxic T lymphocytes that …

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Giant Gallstone, Rare Cause for Conversion to open Cholecystectomy from Laparoscopic

1. Abstract 1.1. Background: Gallbladder stones is one of the most common disease of the digestive system. Giant gallbladder stone is rare and subject to technical difficulties in laparoscopic cholecystectomy with high rate of conversion to open cholecystectomy. 1.2. Aim: This is to report one case of a giant gallstone treated with open technique after …

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