Multi-Drug Resistance (MDR) Imaging by Radiolabeled Paclitaxel

Multidrug resistance (MDR) could be a reason for treatment failure in several cancer patients. MDR refers to a makeup whereby a tumour is immune to an oversized variety of natural chemotherapeutical medicine. Having previous data of the presence of such resistance would decrease morbidity from unsuccessful medical aid and permit for the choice of people UN agency could take pleasure in the coadministration of MDR-inhibiting medicine. The Tc-99m-labeled single-photon-emitting radiotracers sestamibi and tetrofosmin have shown some prophetical worth. However, positron-emitting radiotracers, which permit for dynamic quantitative imaging, hold promise for a additional correct and specific identification of MDRtumors.MDR-expressing tumors ar immune to paclitaxel, that is often used as a chemotherapeutical agent 

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