Issue 8 Articles
A Heterozygous Mutation M694V in the MEFV Gene and HLA-B27 Negative Spondyloarthritis: The Chicken Egg Paradox?
Case Report
1. Abstract There is evidence that the familial Mediterranean gene (MEFV) M694V mutation plays a role in the susceptibility to Spondyloarthritis (SpA). There is an increased prevalence of SpA among Familial Mediterranean fever (FMF) patients, especially in human leukocyte antigen (HLA) B27 negative patients carrying the MEFV M694V mutation.
Pontocerebellar Hypoplasia: Literature Review and Clinical Study
Research Article
AbstractPontocerebellar Hypoplasia (PCH) refers to a group of rare, progressive, and hereditary neurode- generative disorders with prenatal onset. Different subtypes have been identified based on the mu- tations present, and all share common characteristics, such as severe cognitive, linguistic, and motor disabilities.
Intestinal Cystic Pneumatosis : Rare Case
Research Article
1. AbstractIntestinal cystic pneumatosis is a rare condition characterized by the presence of gaseous cysts in the intestinal wall.We report the observation of a 51-year-old patient with dyspepsia syndrome and recurrent episodes of abdominal pain who had a three-day cessation of materials and gas for three days. The clinical ex-...
A Bruise as First Manifestation of Cutaneous Angiosarcoma
Case Report
Cutaneous angiosarcoma is a soft tissue sarcoma that presents as a violaceous plaque, resembling a persistent bruise on the head and neck. The hematoma-like lesions are pitfalls that could be the first spy of malignant vascular tumors. The low survival rates of cutaneous angiosarcoma require a rec ognition as early...
Early Repair of Vesicovaginal Fistula
Research Article
1.1. Background: Vesicovaginal fistula is a common acquired fistula in obstetrics and gynecology. With the development of obstetric technology, the main cause of vesicovaginal fistula is benign gynecological operation. About 80% of vesicovaginal fistula the caused by abdominal hysterecto- my.

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